Bioavailability of folic acid in fortified food
نویسندگان
چکیده
منابع مشابه
High-Performance Liquid Chromatography Method for the Determination of Folic Acid in Fortified Food Products
Reversed-phase high-performance liquid chromatography, coupled with coulometric electrochemical detection, was successfully applied for the quantification of added folic acid (FA) in fortified fruit juices and cereal products. The method allowed good separation of the 5-HCO-H(4) folate and folic acid in cereal samples. The retention times of vitamins were repeatedly determined by isocratic elut...
متن کاملPostprandial serum folic acid response to multiple doses of folic acid in fortified bread.
The benefit of the introduction of mandatory folic acid fortification of all flour products in the USA in 1998 has been amply demonstrated in a reduction of neural tube defect births. Doubt has been cast on the actual level of fortification and recent calculations have shown that the level of folic acid fortification is likely to have been over twice the amount mandated. The implication of this...
متن کاملUnmetabolized folic acid in serum: acute studies in subjects consuming fortified food and supplements.
Periconceptual consumption of folic acid has been shown to decrease the incidence of neural tube defects. The strategy of universal fortification of staple foodstuffs with folic acid presents the possibility of life-long exposure to unmetabolized folic acid. Chief among the risks of exposure to folic acid in the circulation is that of masking the diagnosis of cobalamin deficiency in pernicious ...
متن کاملBioavailability of food folates is 80% of that of folic acid.
BACKGROUND The bioavailability of natural food folates is lower than that of synthetic folic acid, but no agreement exists as to the extent of the difference. OBJECTIVE In a 4-wk dietary intervention study, we determined the aggregate bioavailability of food folates from fruit, vegetables, and liver relative to that of folic acid. DESIGN Seventy-two healthy adults were randomly divided into...
متن کاملBioavailability and bioefficacy of folate and folic acid in man.
Folic acid is important because supplementation around the time of conception has been proven to lower the risk of having offspring with a neural-tube defect. Furthermore, both dietary folate and folic acid decrease plasma total homocysteine concentrations. Elevated plasma homocysteine concentrations are considered to be an independent risk factor for cardiovascular disease. The aim of the pres...
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ژورنال
عنوان ژورنال: The American Journal of Clinical Nutrition
سال: 1997
ISSN: 0002-9165,1938-3207
DOI: 10.1093/ajcn/66.6.1299